Real Madrid were knocked out of the Copa del Rey quarter-finals by losing to Athletic Bilbao on Thursday.
Alex Berenguer scored the killer winning goal in the 89th minute of the match.
Real Betis went through to the Copa del Rey semi-finals on Thursday with a clean four win over Real Sociedad in the quarter-finals, renewing the sweeping result the Andalusian side had already inflicted on their league rivals.
Goals were scored by Betis Juanmi (12 and 57), Brazilian Willian (83 pk), and Aitor Ruibal (87).
The other teams reaching the semi-finals are Valencia after beating Cadiz 2-1, and Rayo Vallecano who knocked Mallorca with a 1-0 win on Wednesday.